Integrative Program in Statistical Genetics and Systems Biology at UF

Publications

Papers to appear

Pinedo, P. J., C. D. Buergelt, G. A. Donovan, P. Melendez, L. Morel, R. L. Wu, T. Y. Langaee and D. O. Rae, 2008 Association between CARD15/NOD2 gene polymorphisms and paratuberculosis infection in cattle. Journal of Veterinary Microbiology.
Chen, Y. M., G. F. Fu and R. L. Wu, 2008 Integration of functional mapping and delay differential equations to map the genes that regulate circadian rhythms. International Conference on Bioinformatics, Computational Biology, Genomics and Chemoinformatics (peer reviewed).
Li, J. H., K. Han, Y. Li, S. Wu, Y. C. Li and R. L. Wu, 2008 An open-pollinated progeny design for constructing a linkage and linkage disequilibrium map in outcrossing populations. Genetics Research (tentatively accepted).
Yang, J., R. L. Wu and G. Casella, 2008 Nonparametric functional mapping of quantitative trait loci. Biometrics.
He, Q. L., Y. Shen, Y. Chen, Y. Zhou, A. Berg, R. L. Wu and M. R. Huang, 2008 Development of sixteen polymorphic simple sequence repeat markers for Lycoris longituba from expressed sequence tags. Molecular Ecology Note.
Kim, B.-R., L. Zhang, A. Berg, J. Fan and R. L. Wu, 2008 A computational framework for functional clustering of periodic gene expression profiles. Genetics.
Wu, S., T. Liu, H. Y. Li, T. M. Yin, S. Wullschleger, G. A. Tuskan and R. L. Wu, 2008 An improved approach for mapping quantitative trait loci in a pseudo-testcross design: Revisiting a poplar genome study. Bioinformatics and Biology Insights (invited).
Li, Y. C., C. M. Coelho, S. Wu, Y. R. Zeng, Y. Li, B. Hunter, R. A. Dante, B. A. Larkins and R. L. Wu, 2008 A statistical strategy to estimate maternal-zygotic interactions and parent-of-origin effects of QTLs for seed development. PLoS ONE.
Hou, W., H. Y. Li, B. Zhang, M. R. Huang and R. L. Wu, 2008 A nonlinear mixed-effect mixture model for functional mapping of longitudinal traits. Heredity.

2008

Das, K., and R. L. Wu, 2008 A genetic model for predicting the incidence of cancer with age. Theoretical Biology and Medical Modeling 5: 7.
Wang, C. G., Y. Cheng, T. Liu, Q. Li, R. Fillingim, P. Wallace, R. Staud, L. Kaplan and R. L. Wu, 2008 A computational model for sex-specific genetic architecture of complex traits in humans. Molecular Pain 4: 13.
Ma, C.-X., Y. Li and R. L. Wu, 2008 Modeling the genetic control of HIV-1 dynamics after highly active antiretroviral therapy. Current Genomics 9: 1-4.
Cui, Y. H., R. L. Wu, G. Casella and J. Zhu, 2008 Nonparametric functional mapping quantitative trait loci underlying programmed cell death. Statistical Applications in Genetics and Molecular Biology 7: 1, Article 4 (http://www.bepress.com/sagmb/vol7/iss1/art4).
Ma, C.-X., Q. B. Yu, A. Berg, G. F. Fu, J. S. Yap, A. X. Tan, M. Kirst, Y. H. Cui and R. L. Wu, 2008 A statistical model for testing the pleiotropic control of phenotypic plasticity of a count trait. Genetics 179: 627-636.
Zhao, W., and R. L. Wu, 2008 A wavelet-based functional mapping of longitudinal trajectories. Journal of the American Statistical Association 103: 714-725.

2007

Yang, R. Q., H. J. Gao, X. Wang, J. Zhang, Z.-B. Zeng and R. L. Wu, 2006 A semiparametric model for composite functional mapping of dynamic quantitative traits. Genetics 177: 1859-1870.
Coelho, C. M., S. Wu, Y. Li, B. Hunter, R. A. Dante, Y. H. Cui, R. L. Wu and B. A. Larkins, 2007 Identification of quantitative trait loci that affect endoreduplication in Zea mays endosperm. Theoretical and Applied Genetics 115: 1147-1162.
Li, H. Y., Z. W. Huang, S. Wu, J. Y. Gai, Y. R. Zeng and R. L. Wu, 2007 A conceptual framework to mapping quantitative trait loci governing ontogenetic allometry. PLoS ONE 2(8): e1245. doi:10.1371/journal.pone.0001245.
Hou, W., J. S. Yap, S. Wu, T. Liu, J. M. Cheverud and R. L. Wu, 2007 Haplotyping a quantitative trait with a high-density map in experimental crosses. PLoS ONE 2(8): e732. doi:10.1371/journal.pone.0000732 (a UF news release on this paper).
Li, Y. C., Y. Li, S. Wu, K. Han, Z. J. Wang, W. Hou,Y. R. Zeng and R. L. Wu, 2007 Estimation of linkage disequilibria in diploid populations with multilocus dominant markers. Genetics 176: 1879-1892.
Cui, Y., K. L. Sun, X. Fan and R. L. Wu, 2007 Mapping nucleotide sequences that encode complex binary disease traits with HapMap. Current Genomics 8: 307-322.
Yap, J. S., C. G. Wang and R. L. Wu, 2007 A simulation approach for functional mapping of quantitative trait loci that regulate thermal performance curves. PLoS ONE 2(6): e554. doi:10.1371/journal.pone.0000554.
Liu, T., X. L. Liu, Y. M. Chen and R. L. Wu, 2007 A unifying differential equation model for functional genetic mapping of circadian rhythms. Theoretical Biology and Medical Modeling 4: 5.
Wu, S., J. Yang, C. G. Wang and R. L. Wu, 2007 A general quantitative genetic model for haplotyping a complex trait in humans. Current Genomics 8: 343-350.
Wu, J. S, J. Zhu, Y. R. Zeng and R. L. Wu, 2007 Functional mapping of norm reactions to environmental signals. Genetical Research 89: 27-38.
Liu, T., R. J. Todhunter, S. Wu, W. Hou, R. Mateescu, Z. W. Zhang, N. I. Burton-Wurster, G. M. Acland, G. Lust and R. L. Wu, 2007 A random model for mapping imprinted quantitative trait loci in a structured pedigree: An implication for mapping canine hip dysplasia. Genomics 90: 276-284 (feature article).
Wu, R. L., W. Hou, Y. H. Cui, H. Y. Li, T. Liu, S. Wu, C.-X. Ma and Y. R. Zeng, 2007. Mapping the genetic architecture of complex traits with molecular markers. Recent Patents on Nanotechnology 1: 41-49 (invited review article).
Zhao, W., H. Y. Li, W. Hou and R. L. Wu, 2007 Wavelet-based parametric functional mapping of developmental trajectories. Genetics 176: 1811-1821.
Wu, J. S., B. Zhang, Y. H. Cui, W. Zhao, M. R. Huang, Y. R. Zeng, J. Zhu, and R. L. Wu, 2007 Genetic mapping of developmental instability: Design, model and algorithm. Genetics 176: 1187-1196.
Lin, M., W. Hou, H. Y. Li, J. A. Johnson and R. L. Wu, 2007 Modeling interactive quantitative trait nucleotides for drug response. Bioinformatics 23: 1251-1257.
Cui, Y. H., J. M. Cheverud and R. L. Wu, 2007 A statistical model for dissecting genomic imprinting through genetic mapping. Genetica 130: 227-239.
Wu, S., J. Yang and R. L. Wu, 2007 Semiparametric functional mapping of quantitative trait loci governing long-term HIV dynamics. Bioinformatics 23: i569-i576.

2006

Lin, M., and R. L. Wu, 2006 Detecting sequence-sequence interactions for complex diseases. Current Genomics 7: 59-72.
Zhang, L., B. Mukherjee, M. Ghosh and R. L. Wu, 2006 Accounting for population stratification in case-control studies of genetic associations: A Bayesian model. Statistical Modeling 6: 352-372.
Kim, B.-R., R. C. Littell and R. L. Wu, 2006 Clustering the periodic pattern of gene expression using Fourier series approximations. Current Genomics 7: 197-203.
Liu, T., R. J. Todhunter, Q. Lu, L. Schoettinger, H. Y. Li, R. C. Littell, S. Bliss, G. Acland, G. Lust and R. L. Wu, 2006 Extent and distribution of zygotic linkage disequilibrium in canine. Genetics 174: 439-453.
Wu, R. L., M. Lin, W. Zhao, W. Hou, B. Zhang, Q. Zhuge, M. R. Huang and L. A. Xu, 2006 Statistical models for studying the genetic architecture of dynamic complex traits. Journal of Nanjing Forestry University 30: 1-12 (invited review article).
Zeng, Y. R., H. Y. Li, Q. Lu, W. Zhao and R. L. Wu, 2006 A systems biology approach for integrating allometry, ontogeny and plasticity through functional mapping. In: Floriculture, Ornamental and Plant Biotechnology: Advances and Topical Issues. Vol. IV. Edited by Jaime A Teixeira da Silva. Global Science Books, Ikenobe, Japan, pp. 206-212 (invited review article).
Li, H. Y., B.-R. Kim and R. L. Wu, 2006 Identification of quantitative trait nucleotides that regulate cancer growth: A simulation approach. Journal of Theoretical Biology 242: 426-439.
Wu, R. L., and M. Lin, 2006 Functional mapping – A new tool to study the genetic architecture of dynamic complex traits. Nature Reviews Genetics 7: 229-237.
Hou, W., C. W. Garvan, W. Zhao, M. Behnke, F. D. Eyler and R. L. Wu, 2006 A general likelihood model for characterizing cocaine-induced genetic determinants for developmental trajectories in early childhood. Statistics in Medicine 25: 4020-4035.
Lin, M. and R. L. Wu, 2006 A joint model for nonparametric functional mapping of longitudinal trajectories and time-to-events. BMC Bioinformatics 7(1):138.
Wu, R. L., H. Y. Li, M. Lin, S. G. Terra, C. J. Pepine, S. P. McGorray, D. Johnson and J. A. Johnson, 2006 Genetic variants for human obesity as revealed by linkage disequilibrium mapping. Current Genomics 7: 463-468.
Lin, M., W. Zhao and R. L. Wu, 2006 A statistical framework for genetic association studies of power curves in bird flight. Biological Procedures Online 8: 164-174 (featured article).
Cui, Y. H., Q. Lu, J. Cheverud, R. C. Littell and R. L. Wu, 2006 Model for mapping imprinted quantitative trait loci in an inbred F2 design. Genomics 87:543-551.
Cui, Y. H., J. G. Wu, C. H. Shi, J. Zhu, R. C. Littell and R. L. Wu, 2006 Modeling epistatic effects of embryo and endosperm QTL on seed development. Genetical Research 87: 61-71.
Long, F., Y. Q. Chen, J. M. Cheverud and R. L. Wu, 2006 Genetic mapping of allometric scaling laws. Genetical Research 87:207-216.
Wu, S., J. Yang and R. L. Wu, 2006 Multilocus linkage disequilibrium mapping of quantitative trait loci that affect HIV dynamics: A simulation approach. Statistics in Medicine 25: 3826-3849.
Cui, Y. H., J. Zhu and R. L. Wu, 2006 Functional mapping for genetic control of programmed cell death. Physiological Genomics 25: 458-469.
Wu, R. L., and W. Hou, 2006 A hyperspace model to decipher the genetic architecture of developmental processes: Allometry meets ontogeny. Genetics 172: 627-637.

2005

Zhao, W., W. Hou, R. C. Littell and R. L. Wu, 2005 Structured antedependence models for functional mapping of multivariate longitudinal quantitative traits. Statistical Methods in Molecular Genetics and Biology 4, http://www.bepress.com/sagmb/vol4/iss1/art33/.
Wu, R. L., C.-X. Ma, W. Hou, P. Corva and J. F. Medrano, 2005 Functional mapping of quantitative trait loci that interact with the hg gene to regulate growth trajectories in mice. Genetics 171: 239-249.
Wang, Z. H., W. Hou and R. L. Wu, 2005 A statistical model to analyze quantitative trait locus interactions for HIV dynamics from the virus and human genomes. Statistics in Medicine 25: 495-511.
Lin, M., and R. L. Wu, 2005 Theoretical basis for the identification of allelic variants that encode drug efficacy and toxicity. Genetics 170: 919-928.
Lin, M., C. Aqvilonte, J. A. Johnson and R. L. Wu, 2005 Sequencing drug response with HapMap. The Pharmacogenomics Journal 5: 149-156.
Cui, Y. H., and R. L. Wu, 2005 Mapping genome-genome epistasis: A multi-dimensional model. Bioinformatics 21: 2447-2455.
Zhao, W., Y. Q. Chen, G. Casella, J. M. Cheverud and R. L Wu, 2005 A nonstationary model for functional mapping of complex traits. Bioinformatics 21: 2469-2477.
Lin, M., R. L. Wu and J. A. Johnson, 2005 A bivariate functional mapping model for gene identification of drug response for systolic and diastolic blood pressures. Pacific Symposium on Biocomputing (http://helix-web.stanford.edu/psb06/lin.pdf).
Wu, R. L., and C.-X. Ma, 2005 A general framework for statistical linkage analysis in multivalent tetraploids. Genetics 170: 899-907.
Todhunter, R. J., R. Mateescu, G. Lust, N. I. Burton-Wurster, N. L. Dykes, S. P. Bliss, A. J. Williams, M. Vernier-Singer, E. Corey, C. Harjes, R. L. Quaas, Z. Zhang, R. O. Gilbert, D. Volkman, G. Casella, R. L. Wu and G. M. Acland, 2005 Quantitative trait loci for hip dysplasia in a crossbreed canine pedigree.Mammalian Genome 16: 720-730.
Hou, W., C. W. Garvan, W. Zhao, M. Behnke, F. D. Eyler and R. L. Wu, 2005 A generalized model for detecting genetic determinants underlying longitudinal traits with unequally spaced measurements and time-dependent correlated errors. Biostatistics 6: 420-433.
Terra, S. G., S. P. McGorray, R. Wu, D. M. McNamara, L. H. Cavallari, J. R. Walker, M. R. Wallace, B. D. Johnson, C. N. Bairey-Merz, G. Sopko, C. J. Pepine and J. A. Johnson, 2005 Association between b-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study. International Journal of Obesity 29: 746-754.
Cui, Y. H., and R. L. Wu, 2005 Statistical model for characterizing epistatic control of triploid endosperm triggered by maternal and offspring QTLs. Genetical Research 86: 65-75.
Lou, X.-Y., G. Casella, R. J. Todhunter, M. K. C. Yang and Wu, R. L., 2005 A general statistical framework for unifying interval and linkage disequilibrium mapping: Towards high-resolution mapping of quantitative traits. Journal of American Statistical Association 100: 158-171.
Lin, M., C.-X. Ma, W. Zhao, J. M. Cheverud and R. L.Wu, 2005 Mechanistic mapping of ontogenetic growth based on biological principles. Growth, Development and Aging 68: 87-93.

2004

Zhang, L., M. C. K. Yang, M. Gallo-Meagher, X. L. Wang, B. A. Larkins and R. L. Wu, 2004 A statistical model for estimating joint maternal-offspring effects on seed development in autogamous plants. Physiological Genomics 19: 262-269.
Wu, R. L., Z. H. Wang, W. Zhao and J. M. Cheverud, 2004 A mechanistic model for genetic machinery of ontogenetic growth. Genetics 168: 2383–2394.
Liu, T., W. Zhao, L. L. Tian and R. L. Wu, 2005 An algorithm for molecular dissection of tumor progression. Journal of Mathematical Biology 50: 336-354.
Formea, C. M., H. Myers, R. L. Wu, J. Crabtree, J. Silkensen, S. Fujita, W. van der Werf, A. Hemming, A. Reed, R. Howard and J. L. Karlix, 2004 Thiopurine S-methyltrasferase genotypic predicts azathioprine toxicity in kidney transplant recipients. American Journal of Transplantation 4: 1810-1817.
Liu, T., J. A. Johnson, G. Casella and R. L. Wu, 2004 Sequencing complex diseases with HapMap. Genetics 168: 503-511.
Lu, Q., Y. H. Cui and R. L. Wu, 2004 A multilocus likelihood approach to joint modeling of linkage, parental diplotype and gene order in a full-sib family. BMC Genetics 5: 20 (http://www.biomedcentral.com/content/pdf/1471-2156-5-20.pdf).
Zhao, W., J. Zhu, M. Gallo-Meagher and R. L. Wu, 2004 A unified statistical model for functional mapping of genotype by environment interactions for ontogenetic development. Genetics 168: 1751-1762.
Zeng, Y. R., J. S. Wu, and R. L. Wu, 2004 Sequencing Populus: An Impetus for Understanding Tree Biodiversity and Evolution. In: Plant Genome: Biodiversity and Evolution Volume 1, Part B: Phanerogams, A.K. Sharma and A. Sharma (eds). Science Publishers, Inc., Enfield, NH, pp 195-205.
Wu, R. L., and G. Casella, 2004 Statistical genetics: Associating genotypic differences with measurable outcomes. In Statistics: A Guide to the Unknown, edited by J. M. Tanur. Holden-Day, San Francisco, CA.
Wu, R. L., J. E. Grisson, S. E. McKeand and D. M. O'Malley, 2004 Phenotypic plasticity of fine roots and increased plant growth in pines. BMC Ecology 4: 14 (http://www.biomedcentral.com/bmcecol/).
Ma, C.-X., R. L. Wu and G. Casella, 2004 FunMap: Functional mapping of complex traits. Bioinformatics 20: 1808–1811.
Wang, Z. H., and R. L. Wu, 2004 A statistical model for high-resolution mapping of quantitative trait loci determining human HIV-1 dynamics. Statistics in Medicine 23: 3033–3051.
Zhao, W., R. L. Wu, C.-X. Ma and G. Casella, 2004 A fast algorithm for functional mapping of complex traits. Genetics 167: 2133–2137.
Gong, Y., Z. H. Wang, T. Liu, W. Zhao, Y. Zhu, J. A. Johnson and R. L. Wu, 2004 A statistical model for high-resolution mapping of quantitative trait loci affecting pharmacodynamic processes. The Pharmacogenomics Journal 4: 315-321.
Zhao, W., C.-X. Ma, J. M. Cheverud and R. L. Wu, 2004 A unifying statistical model for QTL mapping of genotype-sex interaction for developmental trajectories. Physiological Genomics 19: 218-227.
Cui, Y. H., G. Casella and R. L. Wu, 2004 Mapping quantitative trait locus interactions from the maternal and offspring genomes. Genetics 167: 1017-1026.
Wu, R. L., C.-X. Ma, M. Lin and G. Casella, 2004 A general framework for analyzing the genetic architecture of developmental characteristics. Genetics 166: 1541-1551.
Wu, R. L., C.-X. Ma, M. Lin, Z. H. Wang and G. Casella, 2004 Functional mapping of growth quantitative trait loci using a transform-both-sides logistic model. Biometrics 60: 729-738.
Wu, R. L., C.-X. Ma, J. S. Wu, W. Fang and G. Casella, 2004 Population genetics of heterosis: Effects of Hardy-Weinberg disequilibrium. Silvae Genetica 53: 1-6.
Pearce, D. W., S. B. Rood, and R. L. Wu, 2004 Hormones and shoot growth in a hybrid poplar pedigree: Analyses of a segregating F2 population. Tree Physiology 24: 217–224.
Ma, C.-X., M. Lin, G. Casella, R. C. Littell, T. M. Yin and R. L. Wu, 2004 A statistical model for mapping growth trajectories using dominant markers. Theoretical and Applied Genetics 108: 699–705.
Wu, R. L., C.-X. Ma and G. Casella, 2004 A bivalent polyploid model for mapping quantitative trait loci in outcrossing tetraploids. Genetics 166: 581–595.
Wu, R. L., C. X. Ma and G. Casella, 2004 A mixed polyploid model for linkage analysis in tetraploids. Journal of Computational Biology 11: 562–580.

2003

Cooke, J. E. K., K. A. Brown, R. L. Wu, J. M. Davis, 2003 Gene expression associated with N-induced shifts in resource allocation in poplar. Plant, Cell & Environment 26: 757-770.
Todhunter, R. J., Y. T. Grohn, S. P. Bliss, A. Wilfand, A. J. Williams, M. Vernier-Singer, N. I. Burton-Wurster, N. L. Dykes, R. L. Wu, G. Casella, G. M. Acland and G. Lust, 2003 Multiple radiographic predictors of hip cartilage lesions in 8-month-old dogs. American Journal of Veterinary Research 64: 1472-1478.
Wu, R. L., C.-X. Ma, W. Zhao and G. Casella, 2003 Functional mapping of quantitative trait loci underlying growth rates: A parametric model. Physiological Genomics 14: 241-249.
Lou, X.-Y., R. J. Todhunter, M. Lin, Q. Lu, T. Liu, Z. H. Wang, S. Bliss, G. Casella, A. C. Acland, G. Lust and R. L. Wu, 2003 The extent and distribution of linkage disequilibrium in canine. Mammalian Genome 14: 555-564.
Ma, C. X., G. Casella, R. C. Littell, K. A. I. Khuri and R. L. Wu, 2003 Exponential mapping of quantitative traits governing allometric relationships in organisms. Journal of Mathematical Biology 47: 313–324.
Zhang, Y. Z., R. L. Wu, Y. F. Han and W. L. Yin, 2003 AFLP-based linkage maps in Populus tomentosa. Forest Research 13: 100-110.
Wu, R. L., C.-X. Ma, Y.-X. Lou and G. Casella, 2003 Molecular dissection of allometry, ontogeny and plasticity: A genomic view of developmental biology. BioScience 53: 1041–1047.
Lou, X.-Y., G. Casella, R. C. Littell, M. K. C. Yang and R. L. Wu, 2003 A haplotype-based algorithm for multilocus linkage disequilibrium mapping of quantitative trait loci with epistasis in natural populations. Genetics 163: 1533-1548.
Lin, M., X.-Y. Lou, M. Chang and R. L. Wu, 2003 A general statistical framework for mapping quantitative trait loci in non-model systems: Issue for characterizing linkage phases. Genetics 165: 901-913.
Wu, R. L., C. X. Ma, M. C. K. Yang, M. Chang, U. Santra, S. S. Wu, M. Huang, M. Wang and G. Casella, 2003 Quantitative trait loci for growth in Populus. Genetical Research 81: 51-64.
Todhunter, R. J., S. P. Bliss, G. Casella, R. L. Wu, G. Lust, N. I. Burton-Wurster, A. J. Williams, R. O. Gilbert, and G. M. Acland, 2003 Genetic structure of susceptibility traits for hip dysplasia and microsatellite informativeness of an outcrossed canine pedigree. Journal of Heredity 94: 39-48.
Zhu, Y., W. Hou and R. L. Wu, 2003 A haplotype block model for fine mapping of quantitative trait loci regulating HIV-1 pathogenesis. Journal of Theoretical Medicine 5: 1-7.

2002

Wu, R. L., C.-X. Ma and G. Casella, 2002 A bivalent polyploid model for linkage analysis in outcrossing tetraploid species. Theoretical Population Biology 62: 129–151.
Wu, R. L., C. X. Ma, R. C. Littell and G. Casella, 2002 A statistical model for the genetic origin of allometric scaling laws in biology. Journal of Theoretical Biology 217: 275-287.
Wu, R. L., X.-Y. Lou, C.-X. Ma, X. L. Wang, B. A. Larkins and G. Casella, 2002 An improved genetic model generates high-resolution mapping of QTL for protein quality in maize endosperm. Proceedings of the National Academy of Sciences of the United States of America 99: 11281–11286.
Wu, R. L., C.-X. Ma, M. Gallo-Meagher, R. C. Littell and G. Casella, 2002 Statistical methods for dissecting triploid endosperm traits using molecular markers: An autogamous model. Genetics 162: 875-892.
Ma, C. X., G. Casella, and R. L. Wu, 2002 Functional mapping of quantitative trait loci underlying the character process: A theoretical framework. Genetics 161: 1751-1762.
Wu, R. L., C. X. Ma, M. Chang, R. C. Littell, S. S. Wu, M. Huang, M. Wang and G. Casella, 2002 A logistic mixture model for detecting major genes governing growth trajectories. Genetical Research 79:235-245 (the first two authors contribute equally to this work).
Ma, C.-X., G. Casella, Z. J. Shen, T. C. Osborn and R. L. Wu, 2002 A unified framework for mapping quantitative trait loci in bivalent tetraploids using single-dose restriction fragments: A case study from alfalfa. Genome Research 12: 1974-1981.
Wu, R. L., C.-X. Ma and G. Casella, 2002 Joint linkage and linkage disequilibrium mapping of quantitative trait loci in natural populations. Genetics 160: 779-792.
Wu, R. L., C. X. Ma, S. S. Wu and Z-B. Zeng, 2002 Linkage mapping of sex-specific differences. Genetical Research 79: 85-96.
Wu, R. L., C.-X. Ma, I. Painter and Z.-B. Zeng, 2002 Simultaneous maximum likelihood estimation of linkage and linkage phases in outcrossing species. Theoretical Population Biology 61: 349-363.
Wu, S. S., C. X. Ma, R. L. Wu and G. Casella, 2002 A hierarchical statistical model for estimating population properties of quantitative genes. BMC Genetics 3:1-7 (http://www.biomedcentral.com/1471-2156/3/10).
Bliss, S., R. J. Todhunter, R. Quaas, G. Casella, R. L. Wu, G. Lust, A. J. Williams, S. Hamilton, N. L. Dykes, A. Yeager, R. O. Gilbert, N. I. Burton-Wurster and G. M. Acland, 2002 Quantitative genetics of traits associated with canine hip dysplasia in a canine pedigree constructed by mating dysplastic Labrador Retrievers with unaffected Greyhounds. American Journal of Veterinary Research 63: 1029-1035.
Zhang, B., T. M. Yin, Q. Zhuge, Z. M. Han, M. X. Wang, R. L. Wu and M. R. Huang, 2002 Detection of genes affecting fusiform diseases in poplars using molecular markers. Hereditas (Beijing) 23: 400-404.
Yin, T. M., X. Y. Zhang, M. R. Huang, M. X. Wang, Q. Zhuge, S. M. Tu, L.-H. Zhu and R. L. Wu, 2002 The molecular linkage maps of the Populus genome. Genome 45: 541-555.
Wu, R. L., C.-X. Ma, J. Zhu and G. Casella, 2002 Mapping epigenetic quantitative trait loci (QTL) altering a developmental trajectory. Genome 45: 28-33.
Wu, R. L., H. X. Liu and Y. F. Han, 2002 How does phenotypic plasticity affect crown architecture and development? Scientia Silvae Sinicae 38(4): 141-156.